About Me

I’m Guillaume Le Goc, PhD in physics, currently working as a research associate in the Bouvier lab at the Paris-Saclay Institute of Neuroscience (NeuroPSI).

Research Interest

My PhD project took place in Laboratoire Jean Perrin, CNRS/Sorbonne Université (Paris) in 2017–2021. Entitled Exploration of larval zebrafish internal states using temperature, it focused on the effect of the temperature on larval zebrafish locomotion and brain activity.

You can have a look at my manuscript here (pdf, in french) and my defense slides here (browser-based, in english, allow autoplay media or F to fullscreen).

I’m generally interested in data analysis for animal behavior and neuroscience.


  1. N. Beiza Canelo, H. Moulle, T. Pujol, T. Panier, G. Migault, G. Le Goc, P. Tapie, N. Desprat, H. Straka, G. Debrégeas, V. Bormuth. Magnetic actuation of otoliths allows behavioral and brain-wide neuronal exploration of vestibulo-motor processing in larval zebrafish. Current Biology (2023). (doi, biorxiv, pdf)
  2. S. Wolf*, G. Le Goc*, S. Cocco, G. Debrégeas, R. Monasson. Emergence of time persistence in a data-driven neural network model. eLife (2023). (doi, pdf)
  3. T. L. van der Plas*, J. Tubiana*, G. Le Goc, G. Migault, M. Kunst, H. Baier, V. Bormuth, B. Englitz, G. Debrégeas. Neural assemblies uncovered by generative modeling explain whole-brain activity statistics and reflect structural connectivity. eLife (2023). (doi)
  4. G. Le Goc, J. Lafaye, S. Karpenko, V. Bormuth, R. Candelier, G. Debrégeas. Thermal modulation of Zebrafish exploratory statistics reveals constraints on individual behavioral variability. BMC Biology (2021). (doi, pdf)
  5. S. Karpenko, S. Wolf, J. Lafaye, G. Le Goc, T. Panier, V. Bormuth, R. Candelier, G. Debrégeas. From behavior to circuit modeling of light-seeking navigation in zebrafish larvae. eLife (2020). (doi, pdf)
  6. D. Bowman, T. L. Harte, V. Chardonnet, C. De Groot, S. J. Denny, G. Le Goc, M. Anderson, P. Ireland, D. Cassettari, G. D. Bruce. High-fidelity phase and amplitude control of phase-only computer generated holograms using conjugate gradient minimisation. Optics Express (2017). (doi)

* : equal contribution